Microvascular Intervention Cancer Chemotherapy at Fuda Cancer Hospital, Guangzhou, China
Under local anesthesia, a blood vessel in the root of the thigh pierces with a thin needle; then a thin catheter will be inserted along the opening, which will pass to the site of the tumor and administer the drug. The local concentration of the drug accumulated in the short term after interventional chemotherapy is much higher than after systemic chemotherapy.
The microvascular interventional chemotherapy used at the Fuda Cancer Hospital provides a powerful therapeutic effect, avoiding the multiple side effects caused by systemic chemotherapy.
Currently, the most advanced interventional therapy is the treatment of drug-producing microspheres (trade name "HepaSphere"). HepaSphere is stored in powder form and its diameter can rapidly expand to 200 microns after absorption of chemotherapeutic drugs. The HepaSphere property is very stable, so the particles can remain within the tumor for a long time.
In contrast, a traditional iodinated helix embolization agent is continuously destroyed by exposure to blood flow and flows into surrounding normal tissues, blocking the microvascular inside, which often leads to impaired normal tissue function. In addition, water-soluble chemotherapeutic drugs separate quickly from iodized oil, which means a poor effect of slow release and treatment.
After the vessel supplying the tumor is blocked by the microsphere secreting the drug, the tumor will stop feeding, and then the tumor will lose the potential for further growth. After that, under the influence of osmotic pressure, chemotherapeutic drugs located in the microspheres begin to stand out.
Surrounding tumor cells undergo apoptosis and necrosis several days after drug absorption. The release time of the drug from the microspheres will continue for two weeks.
The cost of interventional chemotherapy is $ 3100.
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