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Cancer therapy by dendritic cells

Cancer therapy by dendritic cells

Studies have shown that new and viable dendritic cells can be introduced into the body in the form of a vaccine. If there is cancer, the vaccination with dendritic cells draws the attention of the immune system to its presence and resumes the work of the corresponding functions. This serves as a means of mobilizing a special power of the immune system, capable of finding and fighting cancer.

Treatment of cancer with dendritic cells is used in the treatment of malignant tumors of the skin, kidneys, prostate, breast, ovaries and the large intestine, as well as glioblastoma, lymphoma, brain cancer, pancreas, liver, stomach, lungs and uterus.

This therapy is approved and officially used in clinics in Spain, Czech Republic, Germany Latvia, China and Belarus.

The cost of treatment with dendritic cells is from $6000, depending on the country, on the patient's condition and on the specificity of the disease.

How does cancer appear

Thousands of abnormal cells appear in the body of any healthy person every day in the process of division - however, this is not cancer. Such cells, along with "strangers", are destroyed by the immune system. Recognition of the "friend or foe", the destruction of "foes" and a return to the initial state are ordinary activities of the immune system, but this does not always happen.

The appearance of a large number of abnormal cells naturally depletes the immune system, reduces the effectiveness of its work. At a certain moment among the abnormal cells appear those that are not recognized by the defense system - this is the starting point for the development of cancer.

Abnormal cells divide many times, mutate again, thereby strengthening their position in the body, while immune cells ignore the process of tumor growth. In such a situation, the immune system requires external correction, that is, training the immune cells to recognize and attack cancer. This approach is called immunotherapy in oncology.

Cancer Immunotherapy

Today, there are quite a few types of cancer immunotherapy, one of which is cancer vaccines. The essence of the method is to stimulate the specific anti-cancer activity of the immune system - to “train” it to respond specifically to the type of cancer cells that are in the patient’s body.

The necessary cells are taken from the patient (most often with blood), "brought up" in the laboratory so that they recognize the specific type of cancer that the patient has, and then returned to the body - thus the vaccine becomes an accurate and effective weapon.

Dendritic cells

One of the varieties of immunotherapeutic vaccines is dendritic. The basis for their manufacture are dendritic cells. It is they who determine which molecules “look suspicious”, then they process them in a specific way and give a ready-made “portrait of a criminal” to T-lymphocytes, which specialize in the destruction of cancer cells.

Dendritic cells are cultured from the patient’s own white blood cells (thus, they are “autologous”), and then after some time they are introduced into the patient’s body as a vaccine. Targeted dendritic vaccines adjust the patient’s immune system to prevent relapse.

Initially, after routine blood sampling, blood is sent to a high-tech medical laboratory, where specially trained biologists and technicians select certain white blood cells (monocytes) from the blood. These cells are then cultured and transformed over a period of seven days into a new generation of dendritic cells. This new generation of vital, activated dendritic cells is re-injected into the patient's body with simple injections.

The success of cancer treatment with dendritic cells has been proven in many cured patients, even with severe (stage 4) forms of cancer and glioblastoma.

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